Aim: Behcet’s syndrome is a chronic multisystem vasculitis of unknown origin with frequent manifestation
of oral and genital ulcerations, ocular and skin lesions and other involvement of the central nervous
system and the gastrointestinal tract. We present a case of Behcet syndrome presenting initially with
isolated oral aphthous ulcers and the aim is to highlight the clinical features and its treatment.
Case Report: A 36 year old female with recurrent aphthous ulcers on the tongue for 2 days with a history
of frequent recurrence. Patient responded initially to topical triamcinolone acetonide and low dose
prednisolone. Two weeks later, there was a recurrence of oral aphthous with erosions on the oral mucosa
with skin and genital lesions. A diagnosis of Erythema Multiforme major was made and patient placed on
a higher dose steroid with resultant healing. There was another recurrence with lip crusting, sore throat,
skin lesions, conjuctival inflammation and genitalia ulcerations. We then made a diagnosis of Behcet’s
syndrome. Patient was placed on Dapsone resulting in complete resolution of the lesions with no
recurrence within and after three months of several recall visits.
Conclusion: A case of Behcet’s syndrome that affected the oral mucosa initially and later, the conjunctiva,
the skin, and the genitalia in a 36 year-old female. Health professionals should be aware of this rare