Orofacial Sarcomas: Analysis of 56 Cases in a Nigerian Population

Authors

  • MA OJO Department of Oral Pathology and Medicine, University of Benin Teaching Hospital, Benin City, Edo State
  • FO Omoregie Department of Oral Pathology and Medicine, University of Benin Teaching Hospital, Benin City, Edo State
  • VE Orikpete Department of Oral Pathology and Medicine, University of Benin Teaching Hospital, Benin City, Edo State

Keywords:

Orofacial sarcomas, epidemiology, histopathology

Abstract

AIM: The aim is to study the epidemiological aspects and histopathological types of orofacial sarcomas in a south-south Nigerian population.
METHODS: A 26-year retrospective review of the clinical and histopathology records and slides of all diagnosed orofacial lesions. The sarcomas were selected among the orofacial malignancies and the age, gender, orofacial sites and the histopathologic types of the lesions were analyzed.
RESULTS: There were 313 (19.1%) cases of orofacial malignancies among the 1642 diagnosed orofacial lesions. There were 56 (17.9%) cases of sarcomas among the orofacial malignancies, with a mean age of 32.8 years and peak age groups were the second and third decades of life. There was no gender predilection and the maxillofacial bones (n = 31, 55.4%) were more commonly involved than the soft tissues (n = 25, 44.6%). The mandible (n = 17, 30.4%) was the most common maxillofacial bone site, while the gingiva (n =7, 12.5%) was the most common soft tissue site. The most common sarcomas were malignant fibrous histiocytoma (n=24, 42.9%), rhabdomyosarcoma (n=8, 14.3%), osteosarcoma (n=6, 10.7%) and chondrosarcoma (n=5, 8.9%).
CONCLUSION: A low prevalence of orofacial sarcomas was observed in this study in a south-south Nigerian population. There was predilection of the lesions for young adults and the mandible, but equal gender distribution of the sarcomas in this study. Malignant fibrous histiocytoma and rhabdomyosarcoma were the most frequently diagnosed orofacial sarcomas

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Published

2020-09-06