• OA Adenekan Department of Ophthalmology, Lagos University Teaching Hospital, Lagos. Nigeria.
  • OT Ilo Department of Ophthalmology, Lagos University Teaching Hospital, Lagos. Nigeria.
  • F Mayaki Department of Ophthalmology, Lagos University Teaching Hospital, Lagos. Nigeria
  • FB Akinsola Department of Ophthalmology, Lagos University Teaching Hospital, Lagos. Nigeria.


Orbito-ocular tumors, Histopathology, Sociodemographic, Clinical profile


Aim: A 10 year retrospective review of the orbito-ocular tumor cases presenting at the tertiary hospital with focus on their clinical patterns and their site, age and sex distribution.
Methodology: This study is a retrospective review of the clinical notes of patients with orbito-ocular tumors that presented between 2010 and 2019. Bio-data, clinical presentation, laterality, duration, clinical diagnosis were extracted. Surgical interventions and histopathology confirmation, where available, were also recorded. Orbito-ocular tumors were classified according to anatomical site. Data obtained were analysed using the Statistical Package for Social Sciences (SPSS), version 22.
Results: A total of 91 cases were recruited with 51 (56%) males and 40(44%) females. The intraocular, orbital, conjunctival, and eye lid tumours accounted for 65(71.4%), 10(11.0%), 8(8.8%) and 8(8.8%) cases respectively. The ages ranged from 9 days to 68 years with a mean age of 8.15 ± 14.54 years. 75(82.4%) of all orbito-ocular tumours were seen in children of ages 16 years and below. Squamous cell carcinoma was the commonest orbito-ocular tumor 4(25%), followed by papilloma 3(18.8%) occurring in adults. The leading malignancy in children was Retinoblastoma in 64(85.3%), followed by dermoid cyst 4(5.3%). Two third 54(59.3%) presented within 6 months of onset. More subjects, 40(44.0%) presented with uniocular Right eye tumor while 39(42.8%) presented with uniocular Left eye tumor and 12(13.2%) presented with bilateral tumors. Leucocoria (44%), mass (27.5%) and proptosis (17.6%) were the commonest presenting complaints. About three-quarter (76.9%) of the reviewed cases had surgical intervention. Most of the clinical diagnoses (80.8%) correlated with the histopathology findings. Conclusion: Retinoblastoma remains the commonest orbito-ocular tumor in childhood while squamous cell carcinoma the commonest in adults. Although our study revealed early presentations of most cases, some proportions of patients still decline surgical interventions. This study also observed that clinical diagnosis at presentation highly correlates with subsequent histological diagnosis. There is still need for counselling and continuous education of patients and their relatives on early presentation and treatment acceptance.