EFFECT OF AQUEOUS EXTRACT OF PUMPKIN LEAF (TELFAIRIA OCCIDENTALIS) AND BITTER LEAF (VERNONIA AMYGDALINA) ON SOME SPERMATOZOA CHARACTERS OF MALE WISTAR RATS
H O Otamere, Dr.
Department of Physiology, Faculty of Basic Medical Sciences, College of Medicine, Ambrose Alli University, Ekpoma, Nigeria
U C Osifo, Dr.
c c Nwaogwugwu, Dr.
J J Balogun, Dr.
U Akpamu, Dr.
M O Ujaddughe, Dr
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Keywords

Infertility
Telfairia occidentalis
Vernonia amygdalina
Spermatozoa

How to Cite

Otamere, H., Osifo, U., Nwaogwugwu, c, Balogun, J., Akpamu, U., & Ujaddughe, M. (2018). EFFECT OF AQUEOUS EXTRACT OF PUMPKIN LEAF (TELFAIRIA OCCIDENTALIS) AND BITTER LEAF (VERNONIA AMYGDALINA) ON SOME SPERMATOZOA CHARACTERS OF MALE WISTAR RATS. ANNALS OF MEDICAL AND SURGICAL PRACTICE, 3(2), 90-97. Retrieved from https://edonmajournal.com/index.php/AMSP/article/view/85
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Abstract

Abstract
Aim: This study examined the effect of Telfairia Occidentalis and Vernonia Amygdalina on spermazoa characteristics of adult Wistar rats.
Method: The twenty four (24) adult Wistar rats used in these experiments were randomly assigned to groups A, B, C, and D. Group A served as control and received normal rat chow and water throughout the experiment while group B, C and D, served as experimental groups. Group B and C received 500mg/kg of aqueous extract of Pumpkin Leaf and Bitter leaf respectively and group D received 500mg/kg body weight of the combined aqueous extract of both Leaves for 14 days. At the end of the experiment, semen examination was done to evaluate sperm parameters.
Result: Result showed that Telfairia Occidentalis has an increasing effect on sperm count, but a reducing effect on sperm motility. Similarly, aqueous leaf extract of Vernonia Amygdalina was observed to increase sperm count, improve sperm morphology but reduce sperm motility. On the other hand, the administration of the combined aqueous extracts of Telfairia Occidentalis and Vernonia Amygdalina produces significant improvement in sperm motility, count and morphology compared to group A, B and C.
Conclusion: The results suggests that Telfairia Occidentalis and Vernonia Amygdalina Leaves might improve some sperm functions, however, their combination has synergistic potential on sperm function and may improve fertility in male wistar rats.

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